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Very Low Numbers of CD4(+)FoxP3(+) Tregs Expanded in Donors via TL1A-Ig and Low Dose IL-2 Exhibit a Distinct Activation / Functional Profile and Suppress GVHD in a Pre-clinical Model
Regulatory T cells (Tregs) are essential for the maintenance of tolerance and immune homeostasis. In allogeneic hematopoietic stem cell transplantation (aHSCT), transfer of appropriate Treg numbers is a promising therapy for the prevention of graft-versus-host disease (GVHD). We have recently report...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biol Blood Marrow Transplant |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6163068/ https://ncbi.nlm.nih.gov/pubmed/29751114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2018.04.026 |
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