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Targeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin

PURPOSE: Human sarcomas are rare and difficult to treat cancerous tumors typically arising from soft tissue or bone. Conversely, carcinomas are the most common cancer subtype in humans and the primary cause of mortality across all cancer patients. While conventional therapeutic modalities can prolon...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol
Main Authors: Oh, Felix, Todhunter, Deborah, Taras, Elizabeth, Vallera, Daniel A, Borgatti, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163021/
https://ncbi.nlm.nih.gov/pubmed/30288129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S160262
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