uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells

Exosomes (Exos) have been reported to promote pre-metastatic niche formation, proliferation, angiogenesis and metastasis. We have investigated the role of uPAR in melanoma cell lines-derived Exos and their pro-angiogenic effects on human microvascular endothelial cells (HMVECs) and endothelial colon...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Mol Life Sci
Main Authors: Biagioni, Alessio, Laurenzana, Anna, Menicacci, Beatrice, Peppicelli, Silvia, Andreucci, Elena, Bianchini, Francesca, Guasti, Daniele, Paoli, Paolo, Serratì, Simona, Mocali, Alessandra, Calorini, Lido, Del Rosso, Mario, Fibbi, Gabriella, Chillà, Anastasia, Margheri, Francesca
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004497/
https://ncbi.nlm.nih.gov/pubmed/33237352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03707-4
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker