Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme

The receptor for the urokinase-type plasminogen activator (uPAR) accounts for many features of cancer progression, and is therefore considered a target for anti-tumoral therapy. Only full length uPAR mediates tumor progression. Matrix-metallo-proteinase-12 (MMP12)-dependent uPAR cleavage results int...

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Bibliografiska uppgifter
Huvudupphovsmän: Laurenzana, Anna, Biagioni, Alessio, D'Alessio, Silvia, Bianchini, Francesca, Chillà, Anastasia, Margheri, Francesca, Luciani, Cristina, Mazzanti, Benedetta, Pimpinelli, Nicola, Torre, Eugenio, Danese, Silvio, Calorini, Lido, Rosso, Mario Del, Fibbi, Gabriella
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2014
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116515/
https://ncbi.nlm.nih.gov/pubmed/25003596
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