The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style

The receptor for the urokinase plasminogen activator (uPAR) is up-regulated in malignant tumors. Historically the function of uPAR in cancer cell invasion is strictly related to its property to promote uPA-dependent proteolysis of extracellular matrix and to open a path to malignant cells. These fea...

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Autori principali: Margheri, Francesca, Luciani, Cristina, Taddei, Maria Letizia, Giannoni, Elisa, Laurenzana, Anna, Biagioni, Alessio, Chillà, Anastasia, Chiarugi, Paola, Fibbi, Gabriella, Rosso1, Mario Del
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039230/
https://ncbi.nlm.nih.gov/pubmed/24681666
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