uPAR Knockout Results in a Deep Glycolytic and OXPHOS Reprogramming in Melanoma and Colon Carcinoma Cell Lines

Urokinase Plasminogen Activator (uPA) Receptor (uPAR) is a well-known GPI-anchored three-domain membrane protein with pro-tumor roles largely shown in all the malignant tumors where it is over-expressed. Here we have exploited the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Ca...

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Main Authors: Biagioni, Alessio, Laurenzana, Anna, Chillà, Anastasia, Del Rosso, Mario, Andreucci, Elena, Poteti, Martina, Bani, Daniele, Guasti, Daniele, Fibbi, Gabriella, Margheri, Francesca
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072355/
https://ncbi.nlm.nih.gov/pubmed/32012858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020308
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