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Targeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin

PURPOSE: Human sarcomas are rare and difficult to treat cancerous tumors typically arising from soft tissue or bone. Conversely, carcinomas are the most common cancer subtype in humans and the primary cause of mortality across all cancer patients. While conventional therapeutic modalities can prolon...

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Publicado en:Clin Pharmacol
Autores principales: Oh, Felix, Todhunter, Deborah, Taras, Elizabeth, Vallera, Daniel A, Borgatti, Antonella
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163021/
https://ncbi.nlm.nih.gov/pubmed/30288129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S160262
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