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Targeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin

PURPOSE: Human sarcomas are rare and difficult to treat cancerous tumors typically arising from soft tissue or bone. Conversely, carcinomas are the most common cancer subtype in humans and the primary cause of mortality across all cancer patients. While conventional therapeutic modalities can prolon...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Pharmacol
Prif Awduron: Oh, Felix, Todhunter, Deborah, Taras, Elizabeth, Vallera, Daniel A, Borgatti, Antonella
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163021/
https://ncbi.nlm.nih.gov/pubmed/30288129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S160262
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