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Bispecific Targeting of EGFR and uPAR in a Mouse Model of Head and Neck Squamous Cell Carcinoma
A deimmunized bispecific anti-cancer agent was constructed to simultaneously target both the overexpressed EGF receptor on carcinomas and urokinase receptor (uPAR), that is found on the endothelial cells of the neovasculature within tumors. Flow cytometry assays were performed confirming that severa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480964/ https://ncbi.nlm.nih.gov/pubmed/22818892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2012.06.002 |
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