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Cell-Based Reporter Release Assay to Determine the Potency of Proteolytic Bacterial Neurotoxins

Despite the implementation of cell-based replacement methods, the mouse lethality assay is still frequently used to determine the activity of botulinum toxin (BoNT) for medical use. One explanation is that due to the use of neoepitope-specific antibodies to detect the cleaved BoNT substrate, the cur...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Toxins (Basel)
Päätekijät: Pathe-Neuschäfer-Rube, Andrea, Neuschäfer-Rube, Frank, Haas, Gerald, Langoth-Fehringer, Nina, Püschel, Gerhard Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162785/
https://ncbi.nlm.nih.gov/pubmed/30189643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10090360
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