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NF-κB-dependent IL-8 induction by prostaglandin E(2) receptors EP(1) and EP(4)

BACKGROUND AND PURPOSE: Recent studies suggested a role for PGE(2) in the expression of the chemokine IL-8. PGE(2) signals via four different GPCRs, EP(1)-EP(4). The role of EP(1) and EP(4) receptors for IL-8 induction was studied in HEK293 cells, overexpressing EP(1) (HEK-EP(1)), EP(4) (HEK-EP(4))...

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Detalhes bibliográficos
Main Authors: Neuschäfer-Rube, F, Pathe-Neuschäfer-Rube, A, Hippenstiel, S, Kracht, M, Püschel, GP
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579289/
https://ncbi.nlm.nih.gov/pubmed/22924768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02182.x
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