Prostaglandin E2 Induces IL-6 and IL-8 Production by the EP Receptors/Akt/NF-κB Pathways in Nasal Polyp-Derived Fibroblasts

PURPOSE: Interleukin 6 (IL-6) and IL-8 participate in the pathogenesis of chronic rhinosinusitis with nasal polyps, and their levels are increased by prostaglandin E2 (PGE2) in different cell types. The purposes of this study were to determine whether PGE2 has any effect on the increase in the level...

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Bibliografiska uppgifter
Huvudupphovsmän: Cho, Jung-Sun, Han, In-Hye, Lee, Hye Rim, Lee, Heung-Man
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161687/
https://ncbi.nlm.nih.gov/pubmed/25229003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2014.6.5.449
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