Prostaglandin E2 Induces IL-6 and IL-8 Production by the EP Receptors/Akt/NF-κB Pathways in Nasal Polyp-Derived Fibroblasts

PURPOSE: Interleukin 6 (IL-6) and IL-8 participate in the pathogenesis of chronic rhinosinusitis with nasal polyps, and their levels are increased by prostaglandin E2 (PGE2) in different cell types. The purposes of this study were to determine whether PGE2 has any effect on the increase in the level...

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Hlavní autoři: Cho, Jung-Sun, Han, In-Hye, Lee, Hye Rim, Lee, Heung-Man
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161687/
https://ncbi.nlm.nih.gov/pubmed/25229003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2014.6.5.449
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