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Role of the ERC motif in the proximal part of the second intracellular loop and the C-terminal domain of the human prostaglandin F(2α) receptor (hFP-R) in G-protein coupling control
The human FP-R (F(2α) prostaglandin receptor) is a Gq-coupled heptahelical ectoreceptor, which is of significant medical interest, since it is a potential target for the treatment of glaucoma and preterm labour. On agonist exposure, it mediates an increase in intracellular inositol phosphate formati...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186721/ https://ncbi.nlm.nih.gov/pubmed/15651980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041321 |
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