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Cell-Based Reporter Release Assay to Determine the Activity of Calcium-Dependent Neurotoxins and Neuroactive Pharmaceuticals

The suitability of a newly developed cell-based functional assay was tested for the detection of the activity of a range of neurotoxins and neuroactive pharmaceuticals which act by stimulation or inhibition of calcium-dependent neurotransmitter release. In this functional assay, a reporter enzyme is...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Pathe-Neuschäfer-Rube, Andrea, Neuschäfer-Rube, Frank, Püschel, Gerhard P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066854/
https://ncbi.nlm.nih.gov/pubmed/33808507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13040247
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