Chargement en cours...

Amplification of GTP-cyclohydrolase 1 gene in Plasmodium falciparum isolates with the quadruple mutant of dihydrofolate reductase and dihydropteroate synthase genes in Ghana

Sulfadoxine-pyrimethamine (SP) is used as malaria chemoprophylaxis for pregnant women and children in Ghana. Plasmodium falciparum resistance to SP is linked to mutations in the dihydropteroate synthase gene (pfdhps), dihydrofolate reductase gene (pfdhfr) and amplification of GTP cyclohydrolase 1 (p...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Osei, Musah, Ansah, Felix, Matrevi, Sena A., Asante, Kwaku P., Awandare, Gordon A., Quashie, Neils B., Duah, Nancy O.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162080/
https://ncbi.nlm.nih.gov/pubmed/30265714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204871
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!