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Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana
BACKGROUND: Artemisinin-based combination therapy (ACT) partner drugs, currently used in Ghana are lumefantrine, amodiaquine and piperaquine. Plasmodium falciparum isolates with reduced susceptibility to these partner drugs may affect treatment outcome. Mutations in pfmdr1 gene is linked to reduced...
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| Publié dans: | Malar J |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7362516/ https://ncbi.nlm.nih.gov/pubmed/32669113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03320-7 |
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