Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana

BACKGROUND: Artemisinin-based combination therapy (ACT) partner drugs, currently used in Ghana are lumefantrine, amodiaquine and piperaquine. Plasmodium falciparum isolates with reduced susceptibility to these partner drugs may affect treatment outcome. Mutations in pfmdr1 gene is linked to reduced...

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Detaylı Bibliyografya
Yayımlandı:Malar J
Asıl Yazarlar: Hodoameda, Peter, Duah-Quashie, Nancy Odurowah, Hagan, Charles Oheneba, Matrevi, Sena, Abuaku, Benjamin, Koram, Kwadwo, Quashie, Neils Ben
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362516/
https://ncbi.nlm.nih.gov/pubmed/32669113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03320-7
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