Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana

BACKGROUND: Artemisinin-based combination therapy (ACT) partner drugs, currently used in Ghana are lumefantrine, amodiaquine and piperaquine. Plasmodium falciparum isolates with reduced susceptibility to these partner drugs may affect treatment outcome. Mutations in pfmdr1 gene is linked to reduced...

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Foilsithe in:Malar J
Main Authors: Hodoameda, Peter, Duah-Quashie, Nancy Odurowah, Hagan, Charles Oheneba, Matrevi, Sena, Abuaku, Benjamin, Koram, Kwadwo, Quashie, Neils Ben
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2020
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362516/
https://ncbi.nlm.nih.gov/pubmed/32669113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03320-7
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