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Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives

O-acetylserine sulfhydrylase (OASS) is the pyridoxal 5′-phosphate dependent enzyme that catalyses the formation of L-cysteine in bacteria and plants. Its inactivation is pursued as a strategy for the identification of novel antibiotics that, targeting dispensable proteins, holds a great promise for...

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Détails bibliographiques
Publié dans:J Enzyme Inhib Med Chem
Auteurs principaux: Franko, Nina, Grammatoglou, Konstantinos, Campanini, Barbara, Costantino, Gabriele, Jirgensons, Aigars, Mozzarelli, Andrea
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161599/
https://ncbi.nlm.nih.gov/pubmed/30251899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1504040
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