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Ketamine and Ceftriaxone-Induced Alterations in Glutamate Levels Do Not Impact the Specific Binding of Metabotropic Glutamate Receptor Subtype 5 Radioligand [(18)F]PSS232 in the Rat Brain
Several studies showed that [(11)C]ABP688 binding is altered following drug-induced perturbation of glutamate levels in brains of humans, non-human primates and rats. We evaluated whether the fluorinated derivative [(18)F]PSS232 can be used to assess metabotropic glutamate receptor 5 (mGluR5) availa...
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| Publicado no: | Pharmaceuticals (Basel) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6161118/ https://ncbi.nlm.nih.gov/pubmed/30158438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph11030083 |
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