Radiation dosimetry of [(18)F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans

PURPOSE: (E)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-(3-(2-[(18)F]-fluoroethoxy)propyl) oxime ([(18)F]-PSS232) is a new PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGlu5), and has shown promising results in rodents and humans. The aim of this study was to estimate the radi...

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Dettagli Bibliografici
Pubblicato in:EJNMMI Res
Autori principali: Sah, Bert-Ram, Sommerauer, Michael, Mu, Linjing, Gonzalez, Gloria Pla, Geistlich, Susanne, Treyer, Valerie, Schibli, Roger, Buck, Alfred, Warnock, Geoffrey, Ametamey, Simon M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2019
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593000/
https://ncbi.nlm.nih.gov/pubmed/31240594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-019-0522-9
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