Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

[Image: see text] Mucin-type O-glycosylation is initiated by a family of polypeptide GalNAc-transferases (GalNAc-Ts) which are type-II transmembrane proteins that contain Golgi luminal catalytic and lectin domains that are connected by a flexible linker. Several GalNAc-Ts, including GalNAc-T4, show...

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Dettagli Bibliografici
Pubblicato in:ACS Cent Sci
Autori principali: de las Rivas, Matilde, Paul Daniel, Earnest James, Coelho, Helena, Lira-Navarrete, Erandi, Raich, Lluis, Compañón, Ismael, Diniz, Ana, Lagartera, Laura, Jiménez-Barbero, Jesús, Clausen, Henrik, Rovira, Carme, Marcelo, Filipa, Corzana, Francisco, Gerken, Thomas A., Hurtado-Guerrero, Ramon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2018
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161044/
https://ncbi.nlm.nih.gov/pubmed/30276263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.8b00488
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