Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation

Protein O-glycosylation is controlled by polypeptide GalNAc-transferases (GalNAc-Ts) that uniquely feature both a catalytic and lectin domain. The underlying molecular basis of how the lectin domains of GalNAc-Ts contribute to glycopeptide specificity and catalysis remains unclear. Here we present t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Lira-Navarrete, Erandi, de las Rivas, Matilde, Compañón, Ismael, Pallarés, María Carmen, Kong, Yun, Iglesias-Fernández, Javier, Bernardes, Gonçalo J. L., Peregrina, Jesús M., Rovira, Carme, Bernadó, Pau, Bruscolini, Pierpaolo, Clausen, Henrik, Lostao, Anabel, Corzana, Francisco, Hurtado-Guerrero, Ramon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432651/
https://ncbi.nlm.nih.gov/pubmed/25939779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7937
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi