Doxorubicin-Conjugated PAMAM Dendrimers for pH-Responsive Drug Release and Folic Acid-Targeted Cancer Therapy

We present here the development of multifunctional doxorubicin (DOX)-conjugated poly(amidoamine) (PAMAM) dendrimers as a unique platform for pH-responsive drug release and targeted chemotherapy of cancer cells. In this work, we covalently conjugated DOX onto the periphery of partially acetylated and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Zhang, Mengen, Zhu, Jingyi, Zheng, Yun, Guo, Rui, Wang, Shige, Mignani, Serge, Caminade, Anne-Marie, Majoral, Jean-Pierre, Shi, Xiangyang
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160908/
https://ncbi.nlm.nih.gov/pubmed/30235881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030162
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge