Doxorubicin-Conjugated PAMAM Dendrimers for pH-Responsive Drug Release and Folic Acid-Targeted Cancer Therapy

We present here the development of multifunctional doxorubicin (DOX)-conjugated poly(amidoamine) (PAMAM) dendrimers as a unique platform for pH-responsive drug release and targeted chemotherapy of cancer cells. In this work, we covalently conjugated DOX onto the periphery of partially acetylated and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmaceutics
Main Authors: Zhang, Mengen, Zhu, Jingyi, Zheng, Yun, Guo, Rui, Wang, Shige, Mignani, Serge, Caminade, Anne-Marie, Majoral, Jean-Pierre, Shi, Xiangyang
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160908/
https://ncbi.nlm.nih.gov/pubmed/30235881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030162
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