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Doxorubicin-Conjugated PAMAM Dendrimers for pH-Responsive Drug Release and Folic Acid-Targeted Cancer Therapy

We present here the development of multifunctional doxorubicin (DOX)-conjugated poly(amidoamine) (PAMAM) dendrimers as a unique platform for pH-responsive drug release and targeted chemotherapy of cancer cells. In this work, we covalently conjugated DOX onto the periphery of partially acetylated and...

詳細記述

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書誌詳細
出版年:Pharmaceutics
主要な著者: Zhang, Mengen, Zhu, Jingyi, Zheng, Yun, Guo, Rui, Wang, Shige, Mignani, Serge, Caminade, Anne-Marie, Majoral, Jean-Pierre, Shi, Xiangyang
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160908/
https://ncbi.nlm.nih.gov/pubmed/30235881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030162
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