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PEG-conjugated PAMAM Dendrimers Mediate Efficient Intramuscular Gene Expression
Generations 5 and 6 (G5 and G6) poly(amidoamine) (PAMAM) dendrimers have been shown to be highly efficient nonviral carriers in in vitro gene delivery. However, their high toxicity and unsatisfied in vivo efficacy limit their applications. In this study, to improve their characteristics as gene deli...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758109/ https://ncbi.nlm.nih.gov/pubmed/19479387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9116-1 |
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