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In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates

The present study compares the use of high generation G3 and low generation G0 Polyamidoamine (PAMAM) dendrimers as drug carriers of naproxen (NAP), a poorly water soluble drug. Naproxen was conjugated to G3 in different ratios and to G0 in a 1:1 ratio via a diethylene glycol linker. A lauroyl chain...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Najlah, Mohammad, Freeman, Sally, Khoder, Mouhamad, Attwood, David, D’Emanuele, Antony
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151491/
https://ncbi.nlm.nih.gov/pubmed/28976921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101661
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