Enhanced Delivery of Therapeutic siRNA into Glioblastoma Cells Using Dendrimer-Entrapped Gold Nanoparticles Conjugated with β-Cyclodextrin

We describe a safe and highly effective non-viral vector system based on β-cyclodextrin (β-CD)-modified dendrimer-entrapped gold nanoparticles (Au DENPs) for improved delivery small interfering RNA (siRNA) to glioblastoma cells. In our approach, we utilized amine-terminated generation 5 poly(amidoam...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nanomaterials (Basel)
Auteurs principaux: Qiu, Jieru, Kong, Lingdan, Cao, Xueyan, Li, Aijun, Wei, Ping, Wang, Lu, Mignani, Serge, Caminade, Anne-Marie, Majoral, Jean-Pierre, Shi, Xiangyang
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869622/
https://ncbi.nlm.nih.gov/pubmed/29495429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8030131
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