Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module

The polygenic nature of complex diseases offers potential opportunities to utilize network-based approaches that leverage the comprehensive set of protein-protein interactions (the human interactome) to identify new genes of interest and relevant biological pathways. However, the incompleteness of t...

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Pubblicato in:Sci Rep
Autori principali: Sharma, Amitabh, Kitsak, Maksim, Cho, Michael H., Ameli, Asher, Zhou, Xiaobo, Jiang, Zhiqiang, Crapo, James D., Beaty, Terri H., Menche, Jörg, Bakke, Per S., Santolini, Marc, Silverman, Edwin K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160419/
https://ncbi.nlm.nih.gov/pubmed/30262855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32173-z
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