Beyond GWAS in COPD: Probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks

OBJECTIVES: To use a systems biology approach to integrate genotype and protein-protein interaction (PPI) data to identify disease network modules associated with chronic obstructive pulmonary disease (COPD) and to perform traditional pathway analysis. METHODS: We used a standard gene-set associatio...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Hum Hered
Autores principales: McDonald, Merry-Lynn Noelle, Mattheisen, Manuel, Cho, Michael H., Liu, Yang-Yu, Harshfield, Benjamin, Hersh, Craig P., Bakke, Per, Gulsvik, Amund, Lange, Christoph, Beaty, Terri H., Silverman, Edwin K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415367/
https://ncbi.nlm.nih.gov/pubmed/25171373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000365589
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares