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Uncovering disease-disease relationships through the incomplete human interactome

According to the disease module hypothesis the cellular components associated with a disease segregate in the same neighborhood of the human interactome, the map of biologically relevant molecular interactions. Yet, given the incompleteness of the interactome and the limited knowledge of disease-ass...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Menche, Jörg, Sharma, Amitabh, Kitsak, Maksim, Ghiassian, Susan, Vidal, Marc, Loscalzo, Joseph, Barabási, Albert-László
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435741/
https://ncbi.nlm.nih.gov/pubmed/25700523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1257601
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