Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

BACKGROUND: No pharmacological therapy exists for calcific aortic valve disease (CAVD), which confers a dismal prognosis without invasive valve replacement. The search for therapeutics and early diagnostics is challenging since CAVD presents in multiple pathological stages. Moreover, it occurs in th...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circulation
Egile Nagusiak: Schlotter, Florian, Halu, Arda, Goto, Shinji, Blaser, Mark C., Body, Simon C., Lee, Lang H., Higashi, Hideyuki, DeLaughter, Daniel M., Hutcheson, Joshua D., Vyas, Payal, Pham, Tan, Rogers, Maximillian A., Sharma, Amitabh, Seidman, Christine E., Loscalzo, Joseph, Seidman, Jonathan G., Aikawa, Masanori, Singh, Sasha A., Aikawa, Elena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160370/
https://ncbi.nlm.nih.gov/pubmed/29588317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.032291
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