Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

BACKGROUND: No pharmacological therapy exists for calcific aortic valve disease (CAVD), which confers a dismal prognosis without invasive valve replacement. The search for therapeutics and early diagnostics is challenging since CAVD presents in multiple pathological stages. Moreover, it occurs in th...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Circulation
Hlavní autoři: Schlotter, Florian, Halu, Arda, Goto, Shinji, Blaser, Mark C., Body, Simon C., Lee, Lang H., Higashi, Hideyuki, DeLaughter, Daniel M., Hutcheson, Joshua D., Vyas, Payal, Pham, Tan, Rogers, Maximillian A., Sharma, Amitabh, Seidman, Christine E., Loscalzo, Joseph, Seidman, Jonathan G., Aikawa, Masanori, Singh, Sasha A., Aikawa, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160370/
https://ncbi.nlm.nih.gov/pubmed/29588317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.032291
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky