Annexin A1–dependent tethering promotes extracellular vesicle aggregation revealed with single–extracellular vesicle analysis

Extracellular vesicles (EVs) including plasma membrane–derived microvesicles and endosomal-derived exosomes aggregate by unknown mechanisms, forming microcalcifications that promote cardiovascular disease, the leading cause of death worldwide. Here, we show a framework for assessing cell-independent...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Rogers, Maximillian A., Buffolo, Fabrizio, Schlotter, Florian, Atkins, Samantha K., Lee, Lang H., Halu, Arda, Blaser, Mark C., Tsolaki, Elena, Higashi, Hideyuki, Luther, Kristin, Daaboul, George, Bouten, Carlijn V.C., Body, Simon C., Singh, Sasha A., Bertazzo, Sergio, Libby, Peter, Aikawa, Masanori, Aikawa, Elena
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494353/
https://ncbi.nlm.nih.gov/pubmed/32938681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb1244
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