Annexin A1–dependent tethering promotes extracellular vesicle aggregation revealed with single–extracellular vesicle analysis

Extracellular vesicles (EVs) including plasma membrane–derived microvesicles and endosomal-derived exosomes aggregate by unknown mechanisms, forming microcalcifications that promote cardiovascular disease, the leading cause of death worldwide. Here, we show a framework for assessing cell-independent...

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Vydáno v:Sci Adv
Hlavní autoři: Rogers, Maximillian A., Buffolo, Fabrizio, Schlotter, Florian, Atkins, Samantha K., Lee, Lang H., Halu, Arda, Blaser, Mark C., Tsolaki, Elena, Higashi, Hideyuki, Luther, Kristin, Daaboul, George, Bouten, Carlijn V.C., Body, Simon C., Singh, Sasha A., Bertazzo, Sergio, Libby, Peter, Aikawa, Masanori, Aikawa, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494353/
https://ncbi.nlm.nih.gov/pubmed/32938681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb1244
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