Annexin A1–dependent tethering promotes extracellular vesicle aggregation revealed with single–extracellular vesicle analysis

Extracellular vesicles (EVs) including plasma membrane–derived microvesicles and endosomal-derived exosomes aggregate by unknown mechanisms, forming microcalcifications that promote cardiovascular disease, the leading cause of death worldwide. Here, we show a framework for assessing cell-independent...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Rogers, Maximillian A., Buffolo, Fabrizio, Schlotter, Florian, Atkins, Samantha K., Lee, Lang H., Halu, Arda, Blaser, Mark C., Tsolaki, Elena, Higashi, Hideyuki, Luther, Kristin, Daaboul, George, Bouten, Carlijn V.C., Body, Simon C., Singh, Sasha A., Bertazzo, Sergio, Libby, Peter, Aikawa, Masanori, Aikawa, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494353/
https://ncbi.nlm.nih.gov/pubmed/32938681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb1244
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