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Analysis of Pedigree Data in Populations with Multiple Ancestries: Strategies for Dealing with Admixture in Caribbean Hispanic Families from the ADSP
Multipoint linkage analysis is an important approach for localizing disease-associated loci in pedigrees. Linkage analysis, however, is sensitive to misspecification of marker allele frequencies. Pedigrees from recently-admixed populations are particularly susceptible to this problem because of the...
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| Wydane w: | Genet Epidemiol |
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| Główni autorzy: | , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6160322/ https://ncbi.nlm.nih.gov/pubmed/29862559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22133 |
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