Analysis of Pedigree Data in Populations with Multiple Ancestries: Strategies for Dealing with Admixture in Caribbean Hispanic Families from the ADSP

Multipoint linkage analysis is an important approach for localizing disease-associated loci in pedigrees. Linkage analysis, however, is sensitive to misspecification of marker allele frequencies. Pedigrees from recently-admixed populations are particularly susceptible to this problem because of the...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Genet Epidemiol
Autori principali: Nafikov, Rafael A., Nato, Alejandro Q., Sohi, Harkirat, Wang, Bowen, Brown, Lisa, Horimoto, Andrea R., Vardarajan, Badri N., Barral, Sandra M., Tosto, Giuseppe, Mayeux, Richard P., Thornton, Timothy A., Blue, Elizabeth, Wijsman, Ellen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160322/
https://ncbi.nlm.nih.gov/pubmed/29862559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22133
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi