Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade

Checkpoint blockade immunotherapy targeting the PD-1/PD-L1 inhibitory axis has produced remarkable results in the treatment of several types of cancer. Whereas cytotoxic T cells are known to provide important antitumor effects during checkpoint blockade, certain cancers with low MHC expression are r...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Hsu, Joy, Hodgins, Jonathan J., Marathe, Malvika, Nicolai, Chris J., Bourgeois-Daigneault, Marie-Claude, Trevino, Troy N., Azimi, Camillia S., Scheer, Amit K., Randolph, Haley E., Thompson, Thornton W., Zhang, Lily, Iannello, Alexandre, Mathur, Nikhita, Jardine, Karen E., Kirn, Georgia A., Bell, John C., McBurney, Michael W., Raulet, David H., Ardolino, Michele
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159991/
https://ncbi.nlm.nih.gov/pubmed/30198904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99317
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