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Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade

Checkpoint blockade immunotherapy targeting the PD-1/PD-L1 inhibitory axis has produced remarkable results in the treatment of several types of cancer. Whereas cytotoxic T cells are known to provide important antitumor effects during checkpoint blockade, certain cancers with low MHC expression are r...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Hsu, Joy, Hodgins, Jonathan J., Marathe, Malvika, Nicolai, Chris J., Bourgeois-Daigneault, Marie-Claude, Trevino, Troy N., Azimi, Camillia S., Scheer, Amit K., Randolph, Haley E., Thompson, Thornton W., Zhang, Lily, Iannello, Alexandre, Mathur, Nikhita, Jardine, Karen E., Kirn, Georgia A., Bell, John C., McBurney, Michael W., Raulet, David H., Ardolino, Michele
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159991/
https://ncbi.nlm.nih.gov/pubmed/30198904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99317
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