Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade

Checkpoint blockade immunotherapy targeting the PD-1/PD-L1 inhibitory axis has produced remarkable results in the treatment of several types of cancer. Whereas cytotoxic T cells are known to provide important antitumor effects during checkpoint blockade, certain cancers with low MHC expression are r...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hsu, Joy, Hodgins, Jonathan J., Marathe, Malvika, Nicolai, Chris J., Bourgeois-Daigneault, Marie-Claude, Trevino, Troy N., Azimi, Camillia S., Scheer, Amit K., Randolph, Haley E., Thompson, Thornton W., Zhang, Lily, Iannello, Alexandre, Mathur, Nikhita, Jardine, Karen E., Kirn, Georgia A., Bell, John C., McBurney, Michael W., Raulet, David H., Ardolino, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159991/
https://ncbi.nlm.nih.gov/pubmed/30198904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99317
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