Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade

Checkpoint blockade immunotherapy targeting the PD-1/PD-L1 inhibitory axis has produced remarkable results in the treatment of several types of cancer. Whereas cytotoxic T cells are known to provide important antitumor effects during checkpoint blockade, certain cancers with low MHC expression are r...

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發表在:J Clin Invest
Main Authors: Hsu, Joy, Hodgins, Jonathan J., Marathe, Malvika, Nicolai, Chris J., Bourgeois-Daigneault, Marie-Claude, Trevino, Troy N., Azimi, Camillia S., Scheer, Amit K., Randolph, Haley E., Thompson, Thornton W., Zhang, Lily, Iannello, Alexandre, Mathur, Nikhita, Jardine, Karen E., Kirn, Georgia A., Bell, John C., McBurney, Michael W., Raulet, David H., Ardolino, Michele
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2018
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159991/
https://ncbi.nlm.nih.gov/pubmed/30198904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99317
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