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Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice

The hemagglutinin protein of H3N2 influenza viruses is the major target of neutralizing antibodies induced by infection and vaccination. However, the virus frequently escapes antibody-mediated neutralization due to mutations in the globular head domain. Five topologically distinct antigenic sites in...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Broecker, Felix, Liu, Sean T. H., Sun, Weina, Krammer, Florian, Simon, Viviana, Palese, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158429/
https://ncbi.nlm.nih.gov/pubmed/30045991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01100-18
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