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Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice

The hemagglutinin protein of H3N2 influenza viruses is the major target of neutralizing antibodies induced by infection and vaccination. However, the virus frequently escapes antibody-mediated neutralization due to mutations in the globular head domain. Five topologically distinct antigenic sites in...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Broecker, Felix, Liu, Sean T. H., Sun, Weina, Krammer, Florian, Simon, Viviana, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158429/
https://ncbi.nlm.nih.gov/pubmed/30045991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01100-18
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