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Extending the Stalk Enhances Immunogenicity of the Influenza Virus Neuraminidase

Influenza viruses express two surface glycoproteins, the hemagglutinin (HA) and the neuraminidase (NA). Anti-NA antibodies protect from lethal influenza virus challenge in the mouse model and correlate inversely with virus shedding and symptoms in humans. Consequently, the NA is a promising target f...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Broecker, Felix, Zheng, Allen, Suntronwong, Nungruthai, Sun, Weina, Bailey, Mark J., Krammer, Florian, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714795/
https://ncbi.nlm.nih.gov/pubmed/31375573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00840-19
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