Antibody Responses toward the Major Antigenic Sites of Influenza B Virus Hemagglutinin in Mice, Ferrets, and Humans

The influenza B virus hemagglutinin contains four major antigenic sites (the 120 loop, the 150 loop, the 160 loop, and the 190 helix) within the head domain. These immunodominant antigenic sites are the main targets of neutralizing antibodies and are subject to antigenic drift. Yet little is known a...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Sun, Weina, Kang, Davina S., Zheng, Allen, Liu, Sean T. H., Broecker, Felix, Simon, Viviana, Krammer, Florian, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321909/
https://ncbi.nlm.nih.gov/pubmed/30381487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01673-18
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