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Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop

The severity of the 2014–2016 ebolavirus outbreak in West Africa expedited clinical development of therapeutics and vaccines though the countermeasures on hand were largely monospecific and lacked efficacy against other ebolavirus species that previously emerged. Recent studies indicate that ebolavi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Janus, Benjamin M., van Dyk, Nydia, Zhao, Xuelian, Howell, Katie A., Soto, Cinque, Aman, M. Javad, Li, Yuxing, Fuerst, Thomas R., Ofek, Gilad
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158212/
https://ncbi.nlm.nih.gov/pubmed/30258051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06113-4
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