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Structural Basis of Broad Ebolavirus Neutralization by a Human Survivor Antibody
The structural features that govern broad-spectrum activity of broadly neutralizing, anti-ebolavirus antibodies (Abs) outside of the internal fusion loop epitope are currently unknown. Here we describe the structure of a broadly neutralizing human monoclonal Ab (mAb), ADI-15946, which was identified...
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| Publié dans: | Nat Struct Mol Biol |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6402988/ https://ncbi.nlm.nih.gov/pubmed/30833785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0191-4 |
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