Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus

Drug combinations are synergistic when their combined efficacy exceeds the sum of the individual actions, but they rarely include ineffective drugs that become effective only in combination. We identified several “enabling pairs” of neutralizing and non-neutralizing anti-ebolavirus monoclonal antibo...

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Publicado no:Cell Rep
Main Authors: Howell, Katie A., Brannan, Jennifer M., Bryan, Christopher, McNeal, Andrew, Davidson, Edgar, Turner, Hannah L., Vu, Hong, Shulenin, Sergey, He, Shihua, Kuehne, Ana, Herbert, Andrew S., Qiu, Xiangguo, Doranz, Benjamin J., Holtsberg, Frederick W., Ward, Andrew B., Dye, John M., Aman, M. Javad
Formato: Artigo
Idioma:Inglês
Publicado em: The Author(s). 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082427/
https://ncbi.nlm.nih.gov/pubmed/28402862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.049
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