Excipients for the Lyoprotection of MAPKAP Kinase 2 Inhibitory Peptide Nano-Polyplexes

Herein, excipients are investigated to ameliorate the deleterious effects of lyophilization on peptide-polymer nano-polyplex (NP) morphology, cellular uptake, and bioactivity. The NPs are a previously-described platform technology for intracellular peptide delivery and are formulated from a cationic...

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Bibliografiska uppgifter
I publikationen:J Control Release
Huvudupphovsmän: Mukalel, Alvin J, Evans, Brian C., Kilchrist, Kameron V., Dailing, Eric A., Burdette, Benjamin, Cheung-Flynn, Joyce, Brophy, Colleen M., Duvall, Craig L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157733/
https://ncbi.nlm.nih.gov/pubmed/29709529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.04.045
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