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MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia
Autologous vein grafts are commonly used for coronary and peripheral artery bypass but have a high incidence of intimal hyperplasia (IH) and failure. We present a nanopolyplex (NP) approach that efficiently delivers a mitogen-activated protein kinase (MAPK)–activated protein (MAPKAP) kinase 2 inhibi...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5371354/ https://ncbi.nlm.nih.gov/pubmed/26062847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa4549 |
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