MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia

Autologous vein grafts are commonly used for coronary and peripheral artery bypass but have a high incidence of intimal hyperplasia (IH) and failure. We present a nanopolyplex (NP) approach that efficiently delivers a mitogen-activated protein kinase (MAPK)–activated protein (MAPKAP) kinase 2 inhibi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Transl Med
Main Authors: Evans, Brian C., Hocking, Kyle M., Osgood, Michael J., Voskresensky, Igor, Dmowska, Julia, Kilchrist, Kameron V., Brophy, Colleen M., Duvall, Craig L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371354/
https://ncbi.nlm.nih.gov/pubmed/26062847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa4549
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker