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Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction

[Image: see text] A platform technology has been developed and tested for delivery of intracellular-acting peptides through electrostatically complexed nanoparticles, or nano-polyplexes, formulated from an anionic endosomolytic polymer and cationic therapeutic peptides. This delivery platform has be...

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Detalles Bibliográficos
Publicado en:ACS Nano
Main Authors: Evans, Brian C., Hocking, Kyle M., Kilchrist, Kameron V., Wise, Eric S., Brophy, Colleen M., Duvall, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2015
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482421/
https://ncbi.nlm.nih.gov/pubmed/26004140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b00491
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