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Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles

INTRODUCTION: Nucleic acids have gained recognition as promising immunomodulatory therapeutics. However, their potential is limited by several drug delivery barriers, and there is a need for technologies that enhance intracellular delivery of nucleic acid drugs. Furthermore, controlled and sustained...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: Garland, Kyle M., Sevimli, Sema, Kilchrist, Kameron V., Duvall, Craig L., Cook, Rebecca S., Wilson, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816657/
https://ncbi.nlm.nih.gov/pubmed/31719925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-019-00571-6
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